Bone mineral density and serum testosterone in chronically trained, high mileage 40–55 year old male runners

K J MacKelvie, J E Taunton, H A McKay and K M Khan

School of Human Kinetics, University of British Columbia, Vancouver, Canada
Faculty of Medicine, University of British Columbia

Correspondence to:
Correspondence to: Dr H A McKay, School of Human Kinetics, University of British Columbia, 6081 University Boulevard, Vancouver, BC V6T 1Z1, Canada email: mckayh{at}unixg.ubc.ca

Objectives—To identify physical activity that is beneficial for the maintenance of bone strength with increasing age by examining the relation between bone mineral density (BMD) and chronic endurance training in men. BMD at the proximal femur, its subregions, and the lumbar spine, and serum testosterone were compared between two groups of long distance runners with more than 20 years of training experience and non-athletic controls.

Methods—Runners (n = 12) were divided into (a) high volume runners (n = 7), running 64–80 km a week, and (b) very high volume runners (n = 5), running more than 95 km a week, and compared with non-athletic male controls, exercising in non-endurance oriented activities two to four times a week. BMD (g/cm²) at the total proximal femur, femoral neck, trochanteric region, and lumbar spine was measured by dual energy x ray absorptiometry. Total testosterone (nmol/l) and free testosterone (pmol/l) in serum were measured by radioimmunoassay from single fasting blood samples.

Results—Height, weight, and age (range = 40–55 years) were not significantly different between groups. The high volume runners had significantly higher BMD at the total proximal femur (1.09 (0.17) v 0.94 (0.056)), femoral neck (0.91 (0.16) v 0.78 (0.071)), and trochanteric region (0.85 (0.14) v 0.73 (0.053)) than controls (p<0.05). The differences in BMD for the proximal femur between the very high volume runners and the other two groups were not significant. There was no difference in lumbar spine BMD, total testosterone, or free testosterone between groups. However, there was a significant negative correlation between total testosterone (r = -0.73, p<0.01) and free testosterone (r = -0.79, p<0.005) and running volume in the distance runners.

Conclusions—Long term distance running with training volumes less than 80 km a week had a positive effect on BMD of the proximal femur. With running volumes greater than 64 km a week, training was inversely related to testosterone levels, but levels remained within the normal range.

Key Words: exercise; bone mineral density; male athletes; runners; endurance training; testosterone

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

• James, W. H. (2001). The data sources which may help strengthen the epidemiological evidence for the hormonal hypothesis of sex determination in man. Hum Reprod 16: 1081-1085 [Abstract] [Full Text]  
• James, W. H (2000). Hormones, offspring sex ratios, and weekly training distances of male runners: implications for overtraining. Br. J. Sports. Med. 34: 474-474 [Full Text]