© 2004 BMJ Publishing Group Ltd & British Association of Sport and Exercise Medicine
SHORT REPORT
Raised concentrations of C reactive protein in anabolic steroid using bodybuilders
Department of Health and Exercise Science, University of Glamorgan, Pontypridd, Wales, UK
Correspondence to:
Correspondence to:
Dr Grace
Department of Health and Exercise Science, School of Applied Sciences, University of Glamorgan, Pontypridd, Mid-Glamorgan, Wales, UK; fgrace2{at}glam.ac.uk
Objective: To examine levels of C reactive protein in users of anabolic androgenic steroids (AAS) compared with age matched control groups consisting of AAS using (but abstinent)/resistance trained and non-drug using/sedentary controls.
Method: Subjects included AAS using bodybuilders (n = 10); bodybuilders who denied AAS use (n = 10); sedentary controls (n = 8). Venous blood was sampled, from which serum concentrations of C reactive protein, male sex hormones, and cardiac troponin T were determined.
Results: A significantly altered hormonal profile in the AAS using group provided indirect confirmation of AAS use. C reactive protein concentrations were significantly (p<0.05) higher in the AAS using bodybuilders. There was no relation between C reactive protein and cardiac troponin T.
Conclusion: AAS using bodybuilders had significantly higher C reactive protein concentrations, indicating a greater propensity to develop peripheral arterial disease.
Keywords: bodybuilding; anabolic androgenic steroids; C reactive protein; thromboembolism
Abbreviations: AAS, anabolic androgenic steroid; CRP, C reactive protein
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