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British Journal of Sports Medicine 2004;38:536-541; doi:10.1136/bjsm.2004.011718
Copyright © 2004 BMJ Publishing Group Ltd & British Association of Sport and Exercise Medicine.

REVIEW

Endocannabinoids and exercise

A Dietrich1, W F McDaniel2

1 Department of Social and Behavioral Sciences, American University of Beirut, Lebanon
2 Georgia College and State University, Milledgeville, GA, USA

Correspondence to:
Correspondence to:
Dr Dietrich
PO Box 11-0236, Riad El-Solh, Beirut 1107-2020, Lebanon; arnedietrich{at}aub.edu.lb
Dr McDaniel
Georgia College and State University, Milledgeville, GA 31061, USA; bill.mcdaniel{at}gcsu.edu

ABSTRACT

Exercise induces changes in mental status, particularly analgesia, sedation, anxiolysis, and a sense of wellbeing. The mechanisms underlying these changes remain unknown. Recent findings show that exercise increases serum concentrations of endocannabinoids, suggesting a possible explanation for a number of these changes. This article provides an overview of this emerging field.

Abbreviations: 2-AG, sn-2-arachidonylglycerol; THC, tetrahydrocannabinol

Keywords: anandamide; analgesia; anxiety; marijuana; running


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