© 2005 BMJ Publishing Group Ltd & British Association of Sport and Exercise Medicine
REVIEW
Do non-steroidal anti-inflammatory drugs adversely affect stress fracture healing? A short review
1 Leicester General Hospital, Leicester, UK
2 Queens Medical Centre, Nottingham, UK
Correspondence to:
Correspondence to:
Dr Wheeler
Leicester General Hospital, University Hospital of Leicester NHS Trust, Department of Sports Medicine, Gwendolen Road, Leicester LE5 4PW, UK; patrickwheeler{at}doctors.org.uk
A literature search was performed to determine whether non-steroidal anti-inflammatory drugs (NSAIDs) adversely affect the healing of stress fractures. Evidence exists from laboratory studies and animal subjects that NSAIDs can affect fracture healing. This link has not been proved or disproved in human subjects, particularly for stress fractures. In view of the high usage of NSAIDs in treating musculoskeletal disorders, research is required to investigate whether the healing of stress fractures is affected by these drugs.
Keywords: non-steroidal anti-inflammatory drugs; stress fracture; healing
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