© 2003 BMJ Publishing Group & British Association of Sport and Exercise Medicine
LEADER
Blood doping
O2MAX, blood doping, and erythropoietin
Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
Correspondence to:
Correspondence to:
Professor Joyner, Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA;
joyner.michael@mayo.edu
Methods (legal and illegal) of increasing total body haemoglobin and thereby
O2MAX are discussed
Keywords:
O2MAX; blood doping; erythropoietin; haemoglobin
| The first 150 words of the full text of this article appear below. |
By the 1930s it was clear that champion endurance athletes had remarkably high maximal O2 uptake (O2MAX).1 In the 1950s, 1960s, and 1970s, classic studies were performed on the physiological determinants of O2MAX and on its key role in endurance performance.2–4 During this time there was much debate on O2 delivery versus O2 extraction as the "limiting factor" for O2MAX.5,6 Observations during this era clearly established the role of maximal cardiac output as a determinant of O2MAX, and very high maximal cardiac output values were seen in champion endurance athletes.2 In addition, the important role of blood volume and total body haemoglobin as determinants of O2MAX also emerged (fig 1
).2,7–9 In an effort to better understand the physiological determinants of O2MAX, studies were then conducted that attempted to manipulate O2 delivery using a variety of approaches
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This article has been cited by other articles:
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Leigh-Smith, S
(2004). Blood boosting. Br. J. Sports. Med.
38: 99-101
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