© 2003 BMJ Publishing Group Ltd. & British Association of Sport and Exercise Medicine
LEADER
Osteoarthritis
Abnormal biomechanics: a precursor or result of knee osteoarthritis?
Monash University, Melbourne, Australia
Correspondence to:
Correspondence to:
Associate Professor Cicuttini, 3rd Floor, 553 St Kilda Rd, Melbourne, Vic 3001, Australia;
flavia.cicuttini@med.monash.edu.au
Biomechanical studies are required to differentiate between the causes and results of knee osteoarthritis
Keywords: knee; osteoarthritis; biomechanics
| The first 150 words of the full text of this article appear below. |
Although osteoarthritis (OA) is a common cause of disability in people over 65 years,1 the causes and pathogenesis of knee OA remain largely unknown. In addition to biological studies, there is increasing interest in the contribution of biomechanical variables in the pathogenesis and management of this disease.2–6
OA of the knee occurs most commonly in the medial tibiofemoral compartment,3 and increased regional load across this compartment’s articular cartilage is believed to be an important factor in the pathogenesis of the disease.2–6 The external knee adduction moment is argued to distribute 60–80% of total intrinsic knee compressive load to the medial tibiofemoral compartment,3 and people with medial tibiofemoral OA tend to walk with larger knee adduction moments than normal subjects, resulting in increased medial compartment pressure.2,7 Despite this, there is no clear evidence to suggest whether biomechanical abnormalities such as increased knee adduction moments cause or occur as a result
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