© 2004 BMJ Publishing Group Ltd & British Association of Sport and Exercise Medicine
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Genedicine
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Continuing my occasional forays into gene technology, I was interested to see that regulatory authorities in China have licensed a gene therapy based treatment. This is the first time anywhere in the world that such a treatment has been authorized.
Although the therapy relates to head and neck squamous cell carcinoma (a huge problem in southern China) the technology is relatively straightforward. The company, SiBiono GeneTech, uses an adenovirus as the vector to insert a gene designed to limit cancer cell growth. The results of trials have been published in the peer reviewed Chinese Medical Journal and show this technique to be dramatically effective compared with conventional radiotherapy. The beauty of the technique is that the virus does not integrate into the cell genome (thereby minimising the risk of leukaemia) but rather confines itself to the malignant cell line. The simplicity of the technique is echoed in the
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