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de Jong Z, Munneke M, Zwinderman AH.Ann Rheum Dis 2004;63:1399–1405
Background: Little is known about the effects of exercise on radiological joint damage of the hands and feet in patients with rheumatoid arthritis.
Research question/s: Does long term high intensity weight bearing exercise cause radiological damage of the joints of the hands and feet in patients with rheumatoid arthritis (RA)?
Subjects: 281 subjects with RA according to the American College of Rheumatology (ACR) criteria.
Experimental procedure: All of the subject were part of a 2-year randomised controlled trial in which the effects of usual care physical therapy (CON = 145) were compared with a high intensity weight bearing exercise programme (EX = 136). The rate of radiological joint damage (Larsen score: 0–200, number of damaged joints) of the hands and feet, disease activity (DAS4 score), drug use, physical capacity, bone mineral density, and attendance
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