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Power athletes
Gene driven power athletes? Genetic variation in muscular strength and power
Department of Biomedical Kinesiology, Faculty of Kinesiology and Rehabilitation Sciences, K.U. Leuven, Tervuursevest 101, B-3001 Leuven, Belgium
Correspondence to:
Correspondence to:
Gaston Beunen
Department of Biomedical Kinesiology, Faculty of Kinesiology and Rehabilitation Sciences, K.U. Leuven, Tervuursevest 101, B-3001 Leuven, Belgium; gaston.beunen@faber.kuleuven.be
Accepted 20 July 2006
Strength phenotypes are under strong genetic control, but much research is still required
Keywords: candidate genes; genetic epidemiology; heritability; linkage study; muscle strength
| The first 150 words of the full text of this article appear below. |
Muscular strength and power are important components of fitness essential for the execution of a variety of daily and sporting activities. Static or isometric strength, explosive strength or power, and dynamic (sometimes called functional) strength are generally considered in epidemiological studies.
Analyses of the genetic determinants of strength provide information concerning the contribution of both genes and environmental factors. Interaction effects between genes and environment (the dependence of weight training response on genes) and the identification of genes or coding variants in relation to strength characteristics are also of interest.
Power and strength show normal variation in the general population, as is typical for quantitative, multifactorial phenotypes that are influenced by both multiple genes (polygenic) and environmental factors. The search for the genetic basis of muscular strength and power is based on two approaches: the unmeasured genotype approach (top down) and the measured genotype approach (bottom up).
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