British Journal of Sports Medicine 2006;40:897-899
LEADER
Exercise in older adults
Decline in large elastic artery compliance with age: a therapeutic target for habitual exercise
1 School for Health, University of Bath, Bath BA2 7AY, UK
2 Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
Correspondence to:
P E Gates
School for Health, University of Bath, Bath BA2 7AY, UK; p.gates@bath.ac.uk
Aerobic exercise can favourably modify arterial compliance in middle-aged and older adults
Keywords: arterial stiffness; ageing; cardiovascular disease; physical activity
| The first 150 words of the full text of this article appear below. |
Cardiovascular diseases are prevalent in industrialised societies, and age is the dominant risk factor for morbidity and mortality.1 Consequently, a primary public health concern is to understand the mechanisms by which ageing is associated with cardiovascular diseases and to establish appropriate prevention and intervention strategies. One putative mechanism that has emerged as an important risk factor for cardiovascular disease is the age-associated decline in large artery compliance.2,3 This single degenerative alteration to the vasculature has profound effects on cardiovascular health, contributing to increased systolic blood pressure and pulse pressure, isolated systolic hypertension, reduced cardiovagal baroreflex sensitivity, increased aortic input impedance, left ventricular hypertrophy and diastolic dysfunction, atherosclerosis, and congestive heart failure.1–4 As such, the age-associated decline in arterial compliance is an important therapeutic target for habitual physical activity in the prevention of cardiovascular diseases. The purpose of this article is to highlight recent studies from our
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
- Full Text
- Full Text (PDF)
-
All Versions of this Article:
bjsm.2004.016782v1
40/11/897 most recent - Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
