Commentary
Commentary on âAcid reflux into the oesophagus does not influence exercise-induced airway narrowing in bronchial asthmaâ
Center for Allergy, Asthma and Immunology, USA; ccrandmd@aol.com
Acid reflux into the oesophagus does not influence exercise-induced airway narrowing in bronchial asthma
| The first 150 words of the full text of this article appear below. |
This paper describes a well-conducted, well-designed, well-referenced and well-written investigation of the impact of oesophageal reflux on exercise-induced bronchospasm.Reflux on exertion has been documented in exercising individuals (10 in study) particularly in running or weight training (reference 13 in text). Previous reports have attempted unsuccessfully to find a correlation between oesophageal reflux and exercise asthma but have been limited by small numbers and absence of controls without exercise asthma. The authors present a statistically powered study with adequate controls. Reflux was established by dual pH probe for proximal and distal reflux with pH<4.0 for at least 60 seconds. Exercise asthma was established by 7 minute cycloergometer challenge with monitoring of spirometry with at least 15% decline in FEVI regarded as positive. Reflux was documented by placing a probe in the distal oesophagus during exercise. Subjects were tested at baseline and after 2 weeks on omeprazole. There was no difference
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