Escin/diethylammonium salicylate/heparin combination gels for the topical treatment of acute impact injuries: a randomised, double blind, placebo controlled, multicentre study

D Wetzel; W Menke; R Dieter; V Smasal; B Giannetti; M Bulitta

doi:10.1136/bjsm.36.3.183

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Original article

Escin/diethylammonium salicylate/heparin combination gels for the topical treatment of acute impact injuries: a randomised, double blind, placebo controlled, multicentre study

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	Abstract	Full	Pdf
Jun 2002	28	42	16
Jul 2002	24	43	8
Aug 2002	8	25	5
Sep 2002	8	16	1
Oct 2002	8	15	1
Nov 2002	7	16	2
Dec 2002	4	18	5
Jan 2003	6	13	6
Feb 2003	6	7	2
Mar 2003	4	7	2
Apr 2003	5	18	2
May 2003	17	9	2
Jun 2003	1	9	0
Jul 2003	17	155	2
Aug 2003	20	27	3
Sep 2003	18	26	2
Oct 2003	25	21	2
Nov 2003	12	15	0
Dec 2003	17	15	1
Jan 2004	14	52	3
Feb 2004	10	18	6
Mar 2004	15	11	4
Apr 2004	15	16	1
May 2004	43	40	7
Jun 2004	47	59	19
Jul 2004	41	68	9
Aug 2004	43	91	6
Sep 2004	31	61	11
Oct 2004	25	52	19
Nov 2004	21	54	14
Dec 2004	16	50	11
Jan 2005	27	67	11
Feb 2005	20	54	18
Mar 2005	23	59	19
Apr 2005	8	49	24
May 2005	9	59	24
Jun 2005	12	52	17
Jul 2005	16	68	18
Aug 2005	21	39	13
Sep 2005	6	59	12
Oct 2005	19	70	21
Nov 2005	16	68	22
Dec 2005	16	53	15
Jan 2006	14	52	13
Feb 2006	19	36	18
Mar 2006	10	39	8
Apr 2006	8	21	14
May 2006	18	38	14
Jun 2006	6	30	7
Jul 2006	7	36	15
Aug 2006	12	28	9
Sep 2006	14	35	30
Oct 2006	13	38	28
Nov 2006	13	45	19
Dec 2006	5	35	11
Jan 2007	10	34	25
Feb 2007	17	31	19
Mar 2007	10	32	20
Apr 2007	44	27	20
May 2007	30	16	11
Jun 2007	21	17	15
Jul 2007	15	19	14
Aug 2007	22	13	7
Sep 2007	26	13	8
Oct 2007	34	13	11
Nov 2007	19	9	9
Dec 2007	11	4	8
Jan 2008	16	7	5
Feb 2008	29	8	8
Mar 2008	20	8	8
Apr 2008	18	9	6
May 2008	22	2	2
Jun 2008	26	13	2
Jul 2008	19	2	4
Aug 2008	28	4	4
Sep 2008	22	15	6
Oct 2008	31	9	9
Nov 2008	22	6	4
Dec 2008	17	8	6
Jan 2009	21	4	4
Feb 2009	25	4	5
Mar 2009	36	2	2
Apr 2009	32	2	3
May 2009	28	4	2
Jun 2009	26	1	0
Jul 2009	32	5	7
Aug 2009	19	7	2
Sep 2009	13	4	1
Oct 2009	34	8	2
Nov 2009	33	10	7
Dec 2009	26	7	7
Jan 2010	22	7	3
Feb 2010	19	1	2
Mar 2010	14	1	2
Apr 2010	17	4	5
May 2010	10	7	1
Jun 2010	27	9	7
Jul 2010	25	8	438
Aug 2010	42	12	3
Sep 2010	20	9	2
Oct 2010	41	7	5
Nov 2010	31	3	7
Dec 2010	12	10	0
Jan 2011	22	4	2
Feb 2011	17	9	4
Mar 2011	41	9	10
Apr 2011	31	2	2
May 2011	30	1	3
Jun 2011	39	6	8
Jul 2011	29	4	4
Aug 2011	31	3	2
Sep 2011	36	3	2
Oct 2011	25	5	0
Nov 2011	44	14	7
Dec 2011	21	30	12
Jan 2012	21	28	11
Feb 2012	26	13	5
Mar 2012	22	12	14
Apr 2012	28	33	22
May 2012	27	35	14
Jun 2012	22	29	15
Jul 2012	17	27	12
Aug 2012	36	26	15
Sep 2012	33	24	14
Oct 2012	55	40	25
Nov 2012	32	19	11
Dec 2012	24	14	13
Jan 2013	48	28	32
Feb 2013	21	17	13
Mar 2013	24	15	15
Apr 2013	36	21	25
May 2013	25	13	9
Jun 2013	27	19	20
Jul 2013	34	37	18
Aug 2013	21	41	15
Sep 2013	32	48	18
Oct 2013	28	52	21
Nov 2013	35	22	13
Dec 2013	28	35	19
Jan 2014	33	56	12
Feb 2014	28	32	12
Mar 2014	35	50	12
Apr 2014	40	69	32
May 2014	27	51	15
Jun 2014	21	62	11
Jul 2014	26	47	8
Aug 2014	22	48	4
Sep 2014	21	60	5
Oct 2014	33	53	7
Nov 2014	22	40	8
Dec 2014	28	43	24
Jan 2015	22	59	15
Feb 2015	30	38	6
Mar 2015	20	68	0
Apr 2015	16	44	5
May 2015	24	47	12
Jun 2015	23	55	6
Jul 2015	21	47	5
Aug 2015	4	49	2
Sep 2015	33	60	16
Oct 2015	18	36	5
Nov 2015	18	33	8
Dec 2015	24	33	4
Jan 2016	30	40	7
Feb 2016	27	31	3
Mar 2016	34	39	16
Apr 2016	11	40	8
May 2016	27	48	7
Jun 2016	13	33	10
Jul 2016	24	24	7
Aug 2016	34	31	2
Sep 2016	32	47	13
Oct 2016	29	36	11
Nov 2016	22	34	14
Dec 2016	22	22	6
Jan 2017	17	35	5
Feb 2017	6	25	2
Mar 2017	2	18	7
Apr 2017	7	38	8
May 2017	3	50	5
Jun 2017	8	28	3
Jul 2017	28	23	3
Aug 2017	29	22	9
Sep 2017	45	35	7
Oct 2017	54	36	5
Nov 2017	52	46	7
Dec 2017	59	43	9
Jan 2018	35	29	6
Feb 2018	41	31	8
Mar 2018	50	44	6
Apr 2018	41	33	18
May 2018	61	53	3
Jun 2018	72	54	10
Jul 2018	42	36	7
Aug 2018	62	48	8
Sep 2018	54	46	9
Oct 2018	60	56	9
Nov 2018	82	76	17
Dec 2018	46	42	5
Jan 2019	55	46	14
Feb 2019	61	58	16
Mar 2019	100	87	28
Apr 2019	78	72	16
May 2019	77	66	6
Jun 2019	105	103	19
Jul 2019	98	83	14
Aug 2019	110	90	14
Sep 2019	116	112	9
Oct 2019	86	80	9
Nov 2019	78	72	12
Dec 2019	88	87	20
Jan 2020	141	133	6
Feb 2020	93	84	17
Mar 2020	71	67	10
Apr 2020	65	51	13
May 2020	71	59	6
Jun 2020	54	44	11
Jul 2020	49	41	15
Aug 2020	78	61	38
Sep 2020	57	53	32
Oct 2020	128	70	77
Nov 2020	41	37	11
Dec 2020	85	79	16
Jan 2021	119	110	9
Feb 2021	79	67	16
Mar 2021	39	37	11
Apr 2021	25	17	4
May 2021	26	25	2
Jun 2021	21	21	5
Jul 2021	13	13	8
Aug 2021	43	43	3
Sep 2021	71	72	14
Oct 2021	76	58	33
Nov 2021	92	82	26
Dec 2021	67	61	7
Jan 2022	57	48	19
Feb 2022	68	62	19
Mar 2022	59	48	22
Apr 2022	61	58	17
May 2022	68	62	19
Jun 2022	74	60	20
Jul 2022	65	53	13
Aug 2022	124	122	18
Sep 2022	108	106	53
Oct 2022	86	70	18
Nov 2022	56	46	9
Dec 2022	50	43	9
Jan 2023	55	49	11
Feb 2023	79	74	12
Mar 2023	68	56	19
Apr 2023	79	61	8
May 2023	92	84	14
Jun 2023	55	53	3
Jul 2023	57	51	12
Aug 2023	87	78	10
Sep 2023	70	68	11
Oct 2023	96	72	14
Nov 2023	114	92	14
Dec 2023	163	12	3
Jan 2024	131	5	4
Feb 2024	84	0	0
Mar 2024	234	17	3
Total	9936	9835	3220

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