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High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis
  1. Kassia S Weston1,
  2. Ulrik Wisløff2,
  3. Jeff S Coombes1
  1. 1School of Human Movement Studies, The University of Queensland, St Lucia, Brisbane, Queensland, Australia
  2. 2Department of Circulation and Medical Imaging, Faculty of Medicine, KG Jebsen Center of Exercise in Medicine at Norwegian University of Science and Technology, Trondheim, Norway
  1. Correspondence to Dr Jeff S Coombes, School of Human Movement Studies, The University of Queensland, Brisbane, Queensland 4072, Australia; jcoombes{at}uq.edu.au

Abstract

Background/Aim Cardiorespiratory fitness (CRF) is a strong determinant of morbidity and mortality. In athletes and the general population, it is established that high-intensity interval training (HIIT) is superior to moderate-intensity continuous training (MICT) in improving CRF. This is a systematic review and meta-analysis to quantify the efficacy and safety of HIIT compared to MICT in individuals with chronic cardiometabolic lifestyle diseases.

Methods The included studies were required to have a population sample of chronic disease, where poor lifestyle is considered as a main contributor to the disease. The procedural quality of the studies was assessed by use of a modified Physiotherapy Evidence Base Database (PEDro) scale. A meta-analysis compared the mean difference (MD) of preintervention versus postintervention CRF (VO2peak) between HIIT and MICT.

Results 10 studies with 273 patients were included in the meta-analysis. Participants had coronary artery disease, heart failure, hypertension, metabolic syndrome and obesity. There was a significantly higher increase in the VO2peak after HIIT compared to MICT (MD 3.03 mL/kg/min, 95% CI 2.00 to 4.07), equivalent to 9.1%.

Conclusions HIIT significantly increases CRF by almost double that of MICT in patients with lifestyle-induced chronic diseases.

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