Article Text

PDF
Effects of hydration and water deprivation on blood viscosity during a soccer game in sickle cell trait carriers
  1. Mor Diaw1,
  2. Abdoulaye samb1,
  3. Saliou Diop2,
  4. Niama Diop Sall3,
  5. Abdoulaye Ba1,
  6. Fallou Cissé1,
  7. Philippe Connes4,5
  1. 1Laboratoire de Physiologie et Explorations fonctionnelles, FMPOS, UCAD, Dakar, Senegal
  2. 2Laboratoire d’hémato-immunologie, FMPOS, UCAD, Dakar, Senegal
  3. 3Laboratoire de biochimie et de biologie moléculaire, FMPOS, UCAD, Dakar, Senegal
  4. 4UMR Inserm 665, Université Paris Diderot/Université des Antilles et de la Guyane, Pointe-à Pitre, Guadeloupe
  5. 5Laboratoire ACTES (EA 3596), Département de physiologie Université des Antilles et de la Guyane, Pointe-à Pitre, Guadeloupe
  1. Correspondence to Philippe Connes, UMR Inserm 665, Université Paris Diderot/Université des Antilles et de la Guyane, Pointe-à Pitre, Guadeloupe; pconnes{at}yahoo.fr

Abstract

The present study compared the changes in blood viscosity, hydration status, body temperature and heart rate between a group of sickle cell trait (SCT) carriers and a control (Cont) group before and after a soccer game performed in two conditions: one with water offered ad libitum (hydration condition; Hyd) and the other one without water (dehydration condition; Dehyd). Blood viscosity and haematocrit per blood viscosity ratio (HVR; an index of red blood cell oxygen transport effectiveness) were measured before and at the end of each game. Resting blood viscosity was greater in the SCT carriers than in the Cont group. The increase of blood viscosity over baseline at the end of the game in the Cont group was similar in the two conditions. In contrast, the change in blood viscosity occurring in SCT carriers during soccer games was dependant on the experimental condition: (1) in Dehyd condition, blood viscosity rose over baseline; (2) in Hyd condition, blood viscosity decreased below resting level reaching Cont values. The Cont group had higher HVR than SCT carriers at rest. HVR remained unchanged in the Cont group at the end of the games, whatever the experimental condition. Although HVR of SCT carriers decreased below baseline at the end of the game performed in Dehyd condition, it increased over resting level in Hyd condition reaching the values of the Cont group. Our study demonstrated that ad libitum hydration in exercising SCT carriers normalises the blood hyperviscosity.

Statistics from Altmetric.com

Footnotes

  • Competing interests None.

  • Ethics approval The National Ethics Committee of Senegal.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • ▸ References to this paper are available online at http://bjsm.bmj.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.