Article Text

PDF
61
A history of multiple concussions does not alter the transcranial doppler-based assessment of the neurovascular coupling response
  1. Jonathan D Smirl1,
  2. Alexander D Wright1,2,3,4,
  3. Kevin Bouilane1,
  4. Kelsey Bryk1,
  5. Paul van Donkelaar4
  1. 1School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, Canada
  2. 2University of British Columbia, Vancouver, Canada
  3. 3University of British Columbia Okanagan, Canada
  4. 4Department of Experimental Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada

Abstract

Objective To determine how a history of 3+ concussions alters elevations in cerebral blood velocity (CBV) in the posterior cerebral artery (PCA) during visual tasks.

Design Retrospective Cohort.

Setting Laboratory.

Participants 136 male contact-sport athletes (19.1±1.4 years, 66 football, 70 hockey) were recruited; 39 presented with 0 previous concussions, 16 with 3+ previous concussions; exclusion criteria included history of concussion within 6 months.

Intervention Transcranial Doppler ultrasound indexed PCA-CBV during a series of visual tasks. Participants closed their eyes (20-seconds) and, when prompted, opened their eyes to complete a visual task (40-seconds). Testing occurred prior to the start of their athletic season. The visual trial raw traces were averaged together to enhance the signal-to-noise ratio of outcome measurements. The independent variable tested was concussion history.

Outcomes Eyes-closed CBV (cm/s), peak elevation in CBV after eyes-open (cm/s), relative change in CBV (%), and total activation during the first 30 seconds of the task (indexed via area under the curve-AUC)

Main results Independent samples T-Tests indicated there were no effects of concussion history on any outcome: Eyes-closed CBV (p=0.950), peak CBV (p=0.903), % CBV elevation (p=0.593), and AUC (p=0.718).

Conclusions A history of multiple concussions does not alter the cerebrovasculature’s ability to maintain nutrient delivery required for visual challenges in cortical areas supplied by the PCA. This is an important finding; despite the long-term neurocognitive deficits associated with a history of concussions, the transcranial Doppler assessment of neurovascular coupling appears intact for this population of younger adult contact-sport athletes.

Competing interests None.

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.