OBJECTIVE: This study tests the hypothesis that microwave hyperthermia treatment (MHT) increases heat shock proteins (HSPs) in the human vastus lateralis muscle.
METHODS: Four sedentary male volunteers participated in this study. The lateral side of thigh of one leg (heated leg) was heated with a microwave generator (2.5 GHz, 150 W) for 20 min. One day after the MHT, a muscle sample was taken from the heated leg. A control sample was taken from the unheated leg on another day of the MHT. For both legs, HSP90, 72 and 27 levels were compared.
RESULTS: The HSP90, 72 and 27 levels in heated legs were significantly higher than those of control legs (P < 0.05).
CONCLUSIONS: Application of MHT can increase levels of several HSPs in human skeletal muscle.
- heat stress
- muscle biopsy
- vastus lateralis muscle
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