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ACTN3 genotype in professional soccer players
  1. Catalina Santiago (catalina.santiago{at}uem.es)
  1. Universidad Europea de Madrid, Spain
    1. Marta González-Freire (martitainef{at}hotmail.com)
    1. Universidad Europea de Madrid, Spain
      1. Luis Serratosa (lserratosa{at}realmadrid.es)
      1. Real Madrid, Medical department, Spain
        1. Francisco J Morate (fjmorate{at}realmadrid.es)
        1. Real Madrid, Medical department, Spain
          1. Tim Meyer (tim.meyer{at}uni-paderborn.de)
          1. Institut für Sportmedizin, Universität Paderborn, Germany
            1. Félix Gómez-Gallego (felix.gomez{at}uem.es)
            1. Universidad Europea de Madrid, Spain
              1. Alejandro Lucia (alejandro.lucia{at}uem.es)
              1. Universidad Europea de Madrid, Spain

                Abstract

                We studied the frequency distribution of alpha-actinin-3 (ACTN3) R577X genotypes in 60 top-level Spanish professional soccer players. Their results were compared with those of 52 elite endurance athletes and 123 sedentary controls. The % distribution of RR and RX genotypes in soccer players (48.3% and 36.7%) was significantly higher and lower, respectively, from controls (28.5% and 53.7%) and endurance athletes (26.5% and 52%) (P = 0.041). Though with notable exceptions, elite soccer players tend to have the sprint/power ACTN3 genotype.

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