Article Text

other Versions

The use of prolotherapy in the sacro-iliac joint
  1. Manuel Cusi (m.cusi{at}
  1. University of Notre Dame Australia, Sydney School of Medicine, Australia
    1. Jeni Saunders (jm.saunders{at}
    1. Sports Medicine Programs, UNSW, Australia
      1. Barbara Hungerford (barbhungerford{at}
      1. Sydney Spine & Pelvis Physiotherapy Centre, Australia
        1. Trish Wisbey-Roth (trish{at}
        1. 'Take Control' Active Rehab, Australia
          1. Phil Lucas (philucas{at}
          1. Pittwater Radiology Group, Australia
            1. Stephen Wilson (stwilson{at}
            1. University of Notre Dame Australia, Sydney School of Medicine, Australia


              Objective: To determine whether prolotherapy is effective in the treatment of deficient load transfer of the SIJ.

              Design: A prospective descriptive study.

              Setting: Authors’ private practice.

              Participants:25 patients who consented to treatment and attended for at least one follow up visit and assessment.

              Study period:From April 2004 to July 2007.

              Intervention:Three injections of hypertonic dextrose solution into the dorsal interosseous ligament of the affected SIJ, under CT control, six weeks apart.

              Main outcome measures: Quebec Back Pain Disability Scale, Roland Morris 24, Roland Morris 24 Multiform questionnaires and clinical examination by two authors independently. Clinical tests include active straight leg raise, sacroiliac joint glide, Stork (Gillet), stance phase and posterior pelvic pain provocation tests.

              Results: All patients included in this study attended for at least one follow up visit at 3, 12 or 24 months. The number of patients at follow up decreased at 12 and 24 months. Functional questionnaires demonstrated significant improvements for those followed up at 3, 12 and 24 months (p < 0.05). Clinical scores showed significant improvement from commencement to three, 12 and 24 months (p < 0.001).

              Conclusions:This descriptive study of prolotherapy in private practice has shown positive clinical outcomes for the 76% of patients who attended the 3 months and 12 months’ follow up visits and for the 32% of patients who attended follow up visits at 24 months. Similar results were found in the Questionnaires (Q, RM and RMM) at 3, 12 and 24 months. The findings of this study warrant further research.

              Trial registration Written informed consent was obtained from all participants in the trial. This was conducted as a practice quality assurance project, and as such did not require ethics approval or trial registration.

              Statistics from

              Request permissions

              If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.