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We read with great interest Tilley et al1 meta-analysis which demonstrates the strong association between tendon pathology and serum lipid profiles. This paper included 17 studies involving 2612 participants who were either controls, or who had verified pathology of the Achilles or rotator cuff tendons. The authors conclude that individuals with abnormal lipid profile are much more likely to develop tendon problems. This paper would seem to respond with a resounding ‘Yes!’ to the question posed in 2010, in the pages of BJSM, by Longo et al2—‘Triglycerides and total serum cholesterol in rotator cuff tears: do they matter?’ Tilley's data suggest that triglycerides and total serum cholesterol matter in Achilles tendinopathy and rupture as well.
The results of …