Basic characteristics of the patients and baseline data (intention to treat)
| Escin 1% (n=54) | Escin 2% (n=51) | Placebo (n=51) | |
|---|---|---|---|
| *Injured/contralateral; †multiple citations possible. | |||
| SD, Standard deviation; Q1, lower quartile; Q3, upper quartile. | |||
| Sex | |||
| Male, n (%) | 37 (68.5) | 34 (66.7) | 41 (80.4) |
| Female, n (%) | 17 (31.5) | 17 (33.3) | 10 (19.6) |
| Age (years) | |||
| Mean (median) | 29.2 (27) | 31.3 (30) | 30.7 (29) |
| SD | 10.10 | 9.92 | 9.07 |
| Q1; Q3 | 22; 33 | 24; 35 | 24; 37 |
| Height (cm) | |||
| Mean (median) | 175.9 (175.5) | 176.6 (176) | 178.8 (179) |
| SD | 10.27 | 10.45 | 8.21 |
| Q1; Q3 | 169; 182 | 170; 185 | 173; 185 |
| Weight (kg) | |||
| Mean (median) | 71.8 (72) | 73.7 (73) | 77.5 (77) |
| SD | 12.30 | 13.97 | 10.45 |
| Q1; Q3 | 63; 82 | 65; 83 | 72; 84 |
| Tenderness injured area (kp/cm2) | |||
| Mean (median) | 2.1 (1.9) | 2.0 (1.9) | 2.0 (1.7) |
| SD | 1.12 | 1.00 | 0.93 |
| Q1; Q3 | 1.4; 2.6 | 1.3; 2.7 | 1.4; 2.6 |
| Tenderness contralateral area (kp/cm2) | |||
| Mean (median) | 4.7 (4.7) | 4.9 (5.0) | 4.5 (4.3) |
| SD | 1.45 | 1.65 | 1.48 |
| Q1; Q3 | 3.5; 5.7 | 3.6; 6.0 | 3.6; 5.4 |
| Ratio of tenderness values* (%) | |||
| Mean (median) | 44.3 (44.4) | 40.2 (39.7) | 43.5 (45.3) |
| SD | 13.80 | 14.09 | 12.60 |
| Q1; Q3 | 34.0; 53.3 | 28.3; 51.3 | 33.3; 51.5 |
| VAS (cm) | |||
| Mean (median) | 2.8 (2.6) | 3.3 (2.7) | 3.3 (3.2) |
| SD | 1.86 | 2.63 | 2.11 |
| Q1; Q3 | 1.4; 4.1 | 0.9; 5.1 | 1.3; 4.9 |
| Sprains† | |||
| n (%) | 4 (7.4) | 7 (13.7) | 7 (13.7) |
| Strains† | |||
| n (%) | 15 (27.8) | 15 (29.4) | 9 (17.6) |
| Contusions† | |||
| n (%) | 36 (66.7) | 30 (58.8) | 36 (70.6) |