Endocrine and metabolic characteristics of control and streptozotocin induced hyperglycaemic rats at the end of the experimental period
| Hyperglycaemic rats | |||
|---|---|---|---|
| Characteristic | Control rats | Sedentary | Trained |
| Values are mean (SD) for number of animals indicated in square brackets. | |||
| *p<0.05 compared with controls. | |||
| Age (weeks) | 15 [20] | 15 [18] | 15 [34] |
| Body weight (g) | |||
| Before testosterone treatment | 153 (3) [20] | 139 (8) [18]* | 132 (12) [34]* |
| After testosterone treatment | 172 (13) [8] | 163 (9) [8]* | 144 (20) [17]* |
| Plasma testosterone concentration (nmol/l) | |||
| Before testosterone treatment | 0.9 (0.2) [20] | 0.9 (0.2) [18] | 1.0 (0.1) [34] |
| After testosterone treatment | 5.7 (1.6) [8] | 4.9 (1.3) [8] | 5.0 (1.3) [17] |
| Fasting plasma concentration | |||
| Glucose (mmol/l) | 7.4 (0.4) [12] | 9.8 (1.4) [18]* | 9.4 (0.8) [34]* |
| Insulin (μU/ml) | 65.4 (2.0) [8] | 50.7 (4.7) [8]* | 49.8 (6.0) [8] |
| Insulin/glucose ratio (U/mol) | 8.84 (0.6) [8] | 5.18 (0.6) [8]* | 4.74 (1.0) [8]* |
| Fatty acids (μmol/l) | 152.8 (66.6) [8] | 247.3 (96.0) [8]* | 182.5 (68.3) [8]* |
| Glycerol (μmol/l) | 78.7 (11.7) [8] | 153.3 (43.5) [8]* | 112.4 (26.7) [8]* |
| Triacylglycerols (mmol/l) | 1.38 (0.2) [8] | 1.46 (0.2) [8] | 1.38 (0.1) [8] |