Glycogen synthase and glycogen phosphorylase activity in extensor digitorum longus muscle
| Glycogen synthase | Glycogen phosphorylase | |||||
|---|---|---|---|---|---|---|
| Group | GSi+d | GSi | GSi % of total activity | GPa+b | GPa | GPa % of total activity |
| Values are mean (SD) and are expressed as μmol/min per g wet weight and as % of the total activity. †p<0.05 sedentary v hyperglycaemic; ‡p<0.05 hyperglycaemic v hyperglycaemic + testosterone; §p<0.05 hyperglycaemic v hyprglycaemic + trained; ¶p<0.05 hyperglycaemic + trained v hyperglycaemic + trained + testosterone; **p<0.05 hyperglycaemic + exercised v hyperglycaemic + exercised + testosterone. | ||||||
| GSi, active portion of glycogen synthase; GSi+d, total glycogen synthase; GPa, active form of glycogen phosphorylase; GPa+b, total phosphorylase activity. | ||||||
| Sedentary | 2.80 (0.3) | 0.79 (0.1) | 27.8 (2.0) | 44.5 (16.4) | 5.0 (1.3) | 11.6 (1.7) |
| Testosterone | 2.38 (0.3) | 0.90 (0.1) | 48.2 (16.3) | 55.4 ( 4.4) | 4.9 (0.2) | 8.8 (0.9) |
| Hyperglycaemic | 0.79 (0.1)† | 0.56 (0.1)† | 72.2 (17.3)† | 37.5 (2.4) | 6.9 (1.1) | 18.5 (2.0) |
| Hyperglycaemic + testosterone | 1.58 (0.2)‡ | 0.67 (0.1)‡ | 43.2 (7.5)‡ | 35.3 (6.8) | 3.4 (1.1)‡ | 9.4 (1.7)‡ |
| Hyperglycaemic + trained | 1.38 (0.1)§ | 0.94 (0.1)§ | 68.4 (7.0)§ | 44.6 (5.5) | 4.7 (0.9)§ | 10.6 (2.2) |
| Hyperglycaemic + trained + testosterone | 1.69 (0.2)¶ | 0.95 (0.2) | 51.3 (3.7) | 49.8 (4.3) | 4.5 (0.5) | 9.0 (0.4) |
| Hyperglycaemic + exercised | 1.50 (0.2) | 1.14 (0.1) | 76.6 (9.4) | 65.3 (5.3) | 7.0 (1.5) | 10.6 (1.9) |
| Hyperglycaemic + exercised + testosterone | 2.28 (0.2)** | 1.41 (0.1)** | 62.3 (6.2) | 46.6 (4.0)** | 5.8 (1.1) | 12.5 (2.7) |