Variable | IRL | PLA | CON | |||
---|---|---|---|---|---|---|
Before | After | Before | After | Before | After | |
Values are mean (SD) (n = 5). | ||||||
*Significantly different change from baseline (p<0.05). | ||||||
IRL, Inspiratory resistive loading; PLA, placebo; CON, control; MIP, maximum inspiratory pressure; MEP, maximum expiratory pressure; SMIP, sustained maximum inspiratory pressure; ΣSMIP, sum of SMIP; PTU, pressure time unit; Time, duration of inspiration. ∼ These variables were not measured in the placebo group because performing the test of incremental respiratory endurance with normal resistance would unblind the study. | ||||||
MIP (cm H2O) | 134 (35) | 180 (39)* | 136 (26) | 140.2 (29) | 127 (40) | 128 (39) |
MEP (cm H2O) | 138 (26) | 144 (26) | 126 (40) | 126 (8) | 117 (21) | 126 (32) |
SMIP (PTU) | 987 (144) | 1303 (212)* | ∼ | ∼ | 897 (231) | 915 (219) |
ΣSMIP (PTU) | 29.6 (3.1) | 40.7 (5.8)* | ∼ | ∼ | 23.9 (1.1) | 24.9 (2.9) |
Time (seconds) | 13.6 (3.0) | 17.4 (1.6)* | ∼ | ∼ | 15.8 (3.6) | 15.8 (4.4) |