Table 3

Effects of glyceryl trinitrate 1.25 mg/day through transdermal patch and rehabilitation versus rehabilitation alone in patients with Achilles tendonitis (adapted from Paoloni et al¹⁸)

Week	Active	Placebo	p Value
All results are adjusted for the baseline (week 0) value.
Pain with activity—all patients
	(n = 29)	(n = 33)
2	1.4	1.6	0.43
6	1.1	1.4	0.22
12	0.9	1.4	0.09
24	0.6	1.0	0.15
Pain at rest—all patients
	(n = 28)	(n = 33)
2	1.2	1.1	0.70
6	0.9	1.1	0.47
12	0.9	1.1	0.31
24	0.8	0.9	0.58
Pain at night—all patients
	(n = 27)	(n = 33)
2	1.5	1.7	0.41
6	1.0	1.2	0.27
12	0.6	0.9	0.058
24	0.6	0.7	0.57
Pain on hopping—by heel
	(n = 37)	(n = 44)
2	3.2	3.2	0.98
6	2.9	3.1	0.68
12	2.3	3.0	0.10
24	1.2	2.1	0.023
Tenderness—all patients
	(n = 29)	(n = 33)
2	1.7	1.7	0.75
6	1.4	1.3	0.68
12	0.8	1.3	0.055
24	0.7	0.7	0.99
Change from baseline in total work—by heel
	(n = 36)	(n = 42)
2	12.1	12.3	0.49
6	12.9	13.2	0.66
12	13.5	13.6	0.90
24	14.9	13.6	0.10
Change from baseline in peak force—by heel
	(n = 36)	(n = 41)
2	2.2	2.2	0.41
6	2.4	2.4	0.54
12	2.6	2.4	0.30
24	2.9	2.5	0.010