GRADE assessment of quality of evidence
| Interventions for reducing sedentary behaviour | |||
|---|---|---|---|
| Outcomes | Illustrative comparative risks* (95% CI) | Number of Participants (studies) | Quality of the evidence (GRADE) |
| Corresponding risk | |||
| Interventions for reducing sedentary behaviour | |||
| Effect of lifestyle interventions | The mean effect of lifestyle interventions in the intervention groups was 24.18 min/day lower (40.66 to 7.70 lower) | 3981 (20 studies) | ⊕⊕⊕⊝ moderate† |
| Intervention duration ≤3 months | The mean effect of lifestyle interventions—intervention duration ≤3 months in the intervention groups was 97.75 min/day lower (121.88 to 73.61 lower) | 297 (5 studies) | ⊕⊕⊕⊕ high |
| Intervention duration 3–6 months | The mean effect of lifestyle interventions—intervention duration 3–6 months in the intervention groups was 8.42 min/day lower (19.05 lower to 2.21 higher) | 1664 (7 studies) | ⊕⊕⊕⊝ moderate‡ |
| Intervention duration >6 months | The mean effect of lifestyle interventions—intervention duration >6 months in the intervention groups was 3.99 min/day lower (21.93 lower to 13.96 higher) | 2040 (8 studies) | ⊕⊕⊕⊝ moderate† |
| Effect of physical activity/sedentary behaviour interventions | The mean effect of physical activity/sedentary behaviour interventions in the intervention groups was 32.51 min/day lower (106.52 lower to 41.50 higher) | 471 (4 studies) | ⊕⊕⊕⊝ moderate† |
| Intervention duration ≤3 months | The mean effect of physical activity/sedentary behaviour interventions—intervention duration ≤3 months in the intervention groups was 54.69 min/day lower (166.60 lower to 57.22 higher) | 214 (3 studies) | ⊕⊝⊝⊝ very low§,¶ |
| Intervention duration 3–6 months | The mean effect of physical activity/sedentary behaviour interventions—intervention duration 3–6 months in the intervention groups was 23.60 min/day higher (0.78 higher to 46.42 higher) | 257 (1 study) | ⊕⊕⊕⊝ moderate** |
| Intervention duration >6 months | No evidence available | 0 (0) | No evidence available |
| Effect of physical activity interventions | The mean effect of physical activity interventions in the intervention groups was 6.08 min/day lower (38.00 lower to 25.84 higher) | 1354 (8 studies) | ⊕⊕⊕⊝ moderate†† |
| Intervention duration ≤3 months | The mean effect of physical activity interventions—intervention duration ≤3 months in the intervention groups was 10.43 min/day lower (49.85 lower to 28.98 higher) | 935 (5 studies) | ⊕⊕⊕⊝ moderate†† |
| Intervention duration 3–6 months | The mean effect of physical activity interventions—intervention duration 3–6 months in the intervention groups was 21.52 min/day lower (103.55 lower to 60.51 higher) | 184 (2 studies) | ⊕⊕⊕⊝ moderate†† |
| Intervention duration >6 months | The mean effect of physical activity interventions—intervention duration >6 months in the intervention groups was 48.60 min/day higher (1.66 to 95.54 higher) | 235 (1 study) | ⊕⊕⊕⊝ moderate‡‡ |
| Effect of sedentary behaviour interventions | The mean effect of sedentary behaviour interventions in the intervention groups was 41.76 min/day lower (78.92 to 4.60 lower) | 62 (2 studies) | ⊕⊕⊝⊝ low§,§§ |
| Intervention duration ≤3 months | The mean effect of sedentary behaviour interventions—intervention duration ≤3 months in the intervention groups was 41.76 min/day lower (78.92 to 4.60 lower) | 62 (2 studies) | ⊕⊕⊝⊝ low§,§§ |
| Intervention duration 3–6 months | No evidence available | 0 (0) | No evidence available |
| Intervention duration >6 months | No evidence available | 0 (0) | No evidence available |
GRADE Working Group grades of evidence.
High quality: Further research is very unlikely to change our confidence in the estimate of effect.
Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate.
Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.
Very low quality: We are very uncertain about the estimate.
*The basis for the assumed risk (eg, the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% CI) is based on the assumed risk in the control group and the relative effect of the intervention (and its 95% CI).
†The majority of studies were of high risk of selection, performance or detection bias.
‡Half of the studies were of high risk for performance bias (no blinding of participants or personnel to the intervention intention).
§The wide CI indicates imprecision of results.
¶All studies were of high risk of performance bias and more than half showed high risk of attrition.
**The study was of high risk of selection bias.
††Studies were of high risk of detection or attrition bias.
‡‡The study was of high risk of detection bias.
§§The studies were of high risk of performance bias, that is, participants and personnel were not blinded.