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Sclerosing polidocanol injections in mid-portion Achilles tendinosis: remaining good clinical results and decreased tendon thickness at 2-year follow-up

  • Sports Medicine
  • Published:
Knee Surgery, Sports Traumatology, Arthroscopy Aims and scope

Abstract

The short-term results after treatment with sclerosing polidocanol injections have been shown to be good in patients with chronic painful mid-portion Achilles tendinosis. This study aimed to evaluate the longer-term effects on tendon thickness, structure and vascularity, patient satisfaction with treatment, and pain during tendon loading activity. Ultrasonography (US) + colour Doppler (CD) was used for evaluation of the tendon, and the patients graded the amount of pain during tendon loading activity on a VAS. Forty-two patient’s tendons (23 men and 19 women, mean age 53 years) with a long duration (mean 32 months) of pain symptoms from mid-portion Achilles tendinosis (US + CD showed a localised thickening, structural changes and neovascularisation), were at three (mean) occasions (6–8 weeks in between) treated with US and CD guided injections of the sclerosing substance polidocanol, targeting the area with neovessels ventral to the tendon. After treatment, 37 patients were satisfied with the results of the treatment and back to previous (before injury) activity level. At the 2-year follow-up (mean 23 months), 38 patients were satisfied with the results of the treatment, and there was a significant reduction in VAS (from 75 to 7; P < 0.05). US showed a significant reduction in the mean mid-portion tendon thickness (from 10 to 8 mm, P < 0.05) and a “more normal” structure. CD showed no, or a few, remaining neovessels in the majority of the successfully treated tendons. In conclusion, treatment with sclerosing polidocanol injections in patients with chronic painful mid-portion Achilles tendinosis showed remaining good clinical results at a 2-year follow-up. Decreased tendon thickness and improved structure after treatment, might indicate a remodelling potential?

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References

  1. Józsa L, Kannus P (1997) Human tendons. Anatomy, physiology, and pathology (ISBN 0–87322-484-1) Human Kinetics

  2. Kvist M (1994) Achilles tendon injuries in athletes. Sports Med 18(3):173–201

    PubMed  CAS  Google Scholar 

  3. Movin T (1998) Aspects of aetiology, pathoanatomy and diagnostic methods in chronic mid-portion Achillodynia [dissertation]. Karolinska Institute Stockholm, Stockholm

    Google Scholar 

  4. Alfredson H, Pietilä T, Jonsson P, Lorentzon R (1998) Heavy-loaded eccentric calf-muscle training for the treatment of chronic Achilles tendinosis. Am J Sports Med 26(3):360–366

    PubMed  CAS  Google Scholar 

  5. Alfredson H, Öhberg L (2005) Sclerosing injections to areas of neovascularisation reduce pain in chronic Achilles tendinopathy: a double-blind randomized controlled trial. Knee Surg Sports Traumatol Arthrosc 13:338–344

    Article  PubMed  Google Scholar 

  6. Öhberg L, Alfredson H (2002) Ultrasound guided sclerosis of neovessels in painful chronic Achilles tendinosis: pilot study of a new treatment. Br J Sports Med 36:173–177

    Article  PubMed  Google Scholar 

  7. Öhberg L, Lorentzon R, Alfredson H (2001) Neovsacularisation in Achilles tendons with painful tendinosis but not in normal tendons: an ultrasonographic investigation. Knee Surg Sports Traumatol Arthrosc 9:233–238

    Article  PubMed  Google Scholar 

  8. Bjur D, Alfredson H, Forsgren S (2005) The innervation pattern of the human Achilles tendon—studies on the normal and tendinosis tendon using markers for general, sensory and sympathetic innervations. Cell Tiss Res 320:201–206

    Article  Google Scholar 

  9. Forsgren S, Danielsson P, Alfredson H (2005) Vascular NK-1R receptor occurrence in normal and chronic painful Achilles and patellar tendons. Studies on chemically unfixed as well as fixed specimens. Regul Pept 126:173–181

    Article  PubMed  CAS  Google Scholar 

  10. Conrad P., Malouf GM., Stacey MC (1995) The Australian polidocanol (aethoxysklerol) study. Results at 2 years. Dermatol Surg 21(4):334–336

    Article  PubMed  CAS  Google Scholar 

  11. Guex JJ (1993) Indications for the sclerosing agent polidocanol. J Dermatol Surg Oncol 19(10):959–961

    PubMed  CAS  Google Scholar 

  12. Winter H, Drager E, Sterry W (2000) Sclerotherapy for treatment of hemangiomas. Dermatol Surg 26(2):105–108

    Article  PubMed  CAS  Google Scholar 

  13. Paavola M, Paakkala T, Kannus P et al (1998) Ultrasonography in the differential diagnosis of Achilles tendon injuries and related disorders. Acta Radiol 39:612–19

    Article  PubMed  CAS  Google Scholar 

  14. Åström M, Gentz CF, Nilsson P et al (1996) Imaging in chronic Achilles tendinopathy: a comparison of ultrasonography, magnetic resonance imaging and surgical findings in 27 histologically verified cases. Skeletal Radiol 25:615–20

    Article  PubMed  Google Scholar 

  15. Terslev L, Qvistgaard E, Torp- Pedersen S, Laetgaard J, Danneskiold- Samsøe B, Bliddal H (2001) Ultrasound and power Doppler findings in jumper’s knee—preliminary Observations. Eur J Ultrasound 13:183–189

    Article  PubMed  CAS  Google Scholar 

  16. Weinberg EP, Adams MJ, Hollenberg GM (1998) Color doppler sonography of patellar tendinosis. Am J Roentgenol 171(3):743–744

    CAS  Google Scholar 

  17. Öhberg L, Lorentzon R, Alfredson H (2004) Eccentric training in patients with chronic Achilles tendinosis normalized tendon structure and decreased thickness at follow-up. Br J Sports Med 38:8–11

    Article  PubMed  Google Scholar 

  18. Alfredson H, Öhberg L. Forsgren S (2003) Is vasculo-neural ingrowth the cause of pain in chronic Achilles tendinosis?—an investigation using ultrasonography and colour doppler, immunohistochemistry, and diagnostic injections. Knee Surg Sports Traumatol Arthrosc 11:334–338

    Article  PubMed  Google Scholar 

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Acknowledgments

Financial support was obtained from the Swedish National Centre for Research in Sports.

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Correspondence to Håkan Alfredson.

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Lind, B., Öhberg, L. & Alfredson, H. Sclerosing polidocanol injections in mid-portion Achilles tendinosis: remaining good clinical results and decreased tendon thickness at 2-year follow-up. Knee Surg Sports Traumatol Arthrosc 14, 1327–1332 (2006). https://doi.org/10.1007/s00167-006-0161-3

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  • DOI: https://doi.org/10.1007/s00167-006-0161-3

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