Abstract
The aim of this work was to demonstrate the relationship between osteoarthritic changes seen on magnetic resonance (MR) images of the patellofemoral (PF) or tibiofemoral (TF) compartments in patients with mild osteoarthritis (OA) of the knee. MR images of the knee were obtained in 105 sib pairs (210 patients) who had been diagnosed with OA at multiple joints. Entry criteria included that the degree of OA in the knee examined should be between a Kellgren and Lawrence score of 2 or 3. MR images were analyzed for the presence of cartilaginous lesions, bone marrow edema (BME) and meniscal tears. The relationship between findings in the medial and lateral aspects of the PF and TF compartments was examined. The number of cartilaginous defects on either side of the PF compartment correlated positively with number of cartilaginous defects in the ipsilateral TF compartment (odds ratio, OR, 55, confidence interval, CI, 7.8–382). The number of cartilaginous defects in the PF compartment correlated positively with ipsilateral meniscal tears (OR 3.7, CI 1.0–14) and ipsilateral PF BME (OR 17, CI 3.8–72). Cartilaginous defects in the TF compartment correlated positively with ipsilateral meniscal tears (OR 9.8, CI 2.5–38) and ipsilateral TF BME (OR 120, CI 6.5–2,221). Osteoarthritic defects lateralize or medialize in the PF and TF compartments of the knee in patients with mild OA.
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References
Harris ED Jr (2001) The bone and joint decade: a catalyst for progress. Arthritis Rheum 44(9):1969–1970
Riyazi N, Meulenbelt I, Kroon HM et al (2004) Evidence for familial aggregation of hand, hip and spine osteoarthritis (OA) but not knee OA in siblings with OA at multiple sites: the GARP study. Ann Rheum Dis Sep 30 (Epub ahead of print) PMID:15458958
Gold GE, McCauley TR, Gray ML, Disler DG (2003) What’s new in cartilage? Radiographics 23(5):1227–1242
Guermazi A, Zaim S, Taouli B et al (2003) MR findings in knee osteoarthritis. Eur Radiol 13(6):1370–1386
Vincken PW, ter Braak BP, van Erkel AR et al (2002) Effectiveness of MR imaging in selection of patients for arthroscopy of the knee. Radiology 223(3):739–746
Felson DT, McLaughlin S, Goggins J et al (2003) Bone marrow edema and its relation to progression of knee osteoarthritis. Ann Intern Med 139(5 Pt 1):330–336
Sharma L, Lou C, Felson DT et al (1999) Laxity in healthy and osteoarthritic knees. Arthritis Rheum 42(5):861–870
Sharma L, Song J, Felson DT et al (2001) The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA 286(2):188–195
Elahi S, Cahue S, Felson DT et al (2000) The association between varus–valgus alignment and patellofemoral osteoarthritis. Arthritis Rheum 43(8):1874–1880
Kellgren JH, Lawrence RC (1957) Radiographic assessment of osteoarthritis. Ann Rheum Dis 16:494–502
Kornaat PR, Ceulemans RY, Kroon HM et al (2004) MRI assessment of knee osteoarthritis: Knee Osteoarthritis Scoring System (KOSS)—inter-observer and intra-observer reproducibility of a compartment-based scoring system. Skeletal Radiol Oct 8 (Epub ahead of print) PMID:15480649
Yulish BS, Montanez J, Goodfellow DB et al (1987) Chondromalacia patellae: assessment with MR imaging. Radiology 164(3):763–766
Mink JH, Deutsch AL (1989) Occult cartilage and bone injuries of the knee: detection, classification, and assessment with MR imaging. Radiology 170(3 Pt 1):823–829
Stoller DW, Martin C, Crues JV III et al (1987) Meniscal tears: pathologic correlation with MR imaging. Radiology 163(3):731–735
Dandy DJ, Jackson RW (1975) Meniscectomy and chondromalacia of the femoral condyle. J Bone Joint Surg Am 57(8):1116–1119
Lewandrowski KU, Muller J, Schollmeier G (1997) Concomitant meniscal and articular cartilage lesions in the femorotibial joint. Am J Sports Med 25(4):486–494
Roos H, Lauren M, Adalberth T et al (1998) Knee osteoarthritis after meniscectomy: prevalence of radiographic changes after twenty-one years, compared with matched controls. Arthritis Rheum 41(4):687–693
Hargreaves BA, Gold GE, Beaulieu CF et al (2003) Comparison of new sequences for high-resolution cartilage imaging. Magn Reson Med 49(4):700–709
Mohr A, Priebe M, Taouli B et al (2003) Selective water excitation for faster MR imaging of articular cartilage defects: initial clinical results. Eur Radiol 13(4):686–689
Kornaat PR, Doornbos J, van der Molen AJ et al (2004) Magnetic resonance imaging of knee cartilage using a water selective balanced steady-state free precession sequence. J Magn Reson Imaging 20(5):850–856
Acknowledgements
Pfizer, Groton, CT, USA, provided generous support for this work. The authors would like to acknowledge the support of the cooperating hospitals and the referring rheumatologists, orthopedic surgeons and general practitioners in our region.
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Kornaat, P.R., Watt, I., Riyazi, N. et al. The relationship between the MRI features of mild osteoarthritis in the patellofemoral and tibiofemoral compartments of the knee. Eur Radiol 15, 1538–1543 (2005). https://doi.org/10.1007/s00330-005-2691-3
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DOI: https://doi.org/10.1007/s00330-005-2691-3