Finite element studies of some juxtarticular stress changes due to localized subchondral stiffening
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2019, Osteoarthritis and CartilageCitation Excerpt :Then, an sBMD value was calculated for each subchondral point of the 3D femur models by averaging the CT intensity in the first 3 mm of bone17,19. A penetration of 3 mm was selected to strictly measure the BMD of the subchondral bone17,38,39. A CTh value was also determined for each subchondral point of the 3D femur models by calculating the distance to the articular surface of the 3D cartilage models36,40.
Shock absorbing ability in healthy and damaged cartilage-bone under high-rate compression
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2017, Osteoarthritis and CartilageCitation Excerpt :Given the clinical evidence of SCB thickening in OA patients, historically, the hypothesis has been that disease initiation is associated with increased mass and apparent stiffening of the SCB plate, diminishing its ability to act as an effective shock absorber for the cartilage8–10. However, recent studies suggest that SCB stiffening may not influence the stresses engendered on the cartilage surface3,11 leading to the conclusion that OA joint pathology initiates in the articular cartilage rather than the SCB. In more advanced stages of OA, abnormal mechanical forces can contribute to articular cartilage loss via the initiation of microcracks in the SCB plate that activate a bone remodeling response, leading to tidemark advancement and subsequent thinning of the cartilage3,12–14.
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Current address: Department of Orthopaedic Surgery, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, U.S.A.
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Department of Orthopaedic Surgery, West Virginia University, Morgantown, WV 26506, U.S.A.