Changes in pulmonary diffusing capacity and closing volume after running a marathon

doi:10.1016/0034-5687(83)90090-7

Respiration Physiology

Volume 52, Issue 3, June 1983, Pages 349-359

Respiration Physiolo...

https://doi.org/10.1016/0034-5687(83)90090-7 Get rights and content

Abstract

The purpose of this study was to evaluate changes in lung function after running a marathon. Pulmonary function tests were administered to 8 men before, immediately after, and the day following competition $X ̄ run time = 3 hr 30 min$ ). Subjects completed maximum expiratory flow volume maneurvers breathing air and 80% He/20% O₂. Lung volumes were determined by N₂ washout and single breath He dilution. Closing volumes (CV) were determined using a single breath O₂ test. Pulmonary diffusing capacity (DL_CO), pulmonary capillary blood volume (Vc), and membrane diffusing capacity (DM) were measured with the single breath technique. There were no changes in lung volumes or flow rates, except for an increase in FEV₁, after the marathon. The He/O₂ ΔV̇max₅₀, ΔV̇max₂₅, and isoflow values were similar pre- compared to post-race. There were significant decreases, however, in DL_CO, DM and increases in CV prost-race. Vc remained similar to pre-race values. These results suggest that small airways obstruction does not occur after a marathon. The significant increase in alveolarcapillary membrane resistance, however, may reflect the occurence of subclinical edema. Such a change would decrease lung elastic recoil and could explain the increase in CV.

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^∗: Present address: Pulmonary Disease Division, Sinai Hospital, Belvedere and Greespring Avenue, Baltimore, MD 21215, U.S.A.

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Changes in pulmonary diffusing capacity and closing volume after running a marathon

Abstract

Chest

Am. J. Med.

Diffusing capacity and interpretation of diffusion effects

West. J. Med.

Variations in the pulmonary capillary blood volume and membrane diffusion component in health and disease

J. Clin. Invest.

A comparison of conventional spirometric tests and the test of closing volume

Am. Rev. Respir. Dis.

The effect of an acute bout of exercise on selected pulmonary function measurements

Med. Sci. Sports Exercise

Evidence of increased thoracic extravascular fluid following intense exercise in man

Physiologist

Changes in lung volume, lung density and distribution of ventilation during hypobaric decompression

J. Appl. Physiol.

The relation between structural changes in small airways and pulmonary-function testss

N. Engl. J. Med.

The use of a helium-oxygen mixture during maximum expiratory flow to demonstrate obstruction in small airways in smokers

J. Clin. Invest.

Epidemiology Standardization Report. III. Recommended standardized procedures for pulmonary fuction testing

Am. Rev. Respir. Dis.

Pulmonary Edema

Snowbird workshop on standardization spirometry. ATS statement

Am. Rev. Respir. Dis.

Observations on a group of marathon runners with special reference to the circulation

Arch. Intern. Med.

Die sportartzlichen Ertahungen vom II. Schweizerischen Marathonlauf 1928

Schweiz. Med. Wochenschr.

Sportartzliche Beobachtungen vom I. Schweizerischen Marathonlauf 1927, unter besonderer Berücksichtigung des Verhaltens der Kreislauforgane und der Atmung

Schweiz. Med. Wochenschr.