Relation of percentage of body fat and maximal aerobic capacity to risk factors for atherosclerosis and diabetes in black and white seven- to eleven-year-old children☆,☆☆,★,★★
Section snippets
METHODS
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Subjects
Complete data were obtained for 57 children 7 to 11 years of age, with a wide range of fatness. Ethnicity was determined by self-designation by the parents. All children and their parents gave informed consent in accordance with procedures of the Medical College of Georgia Human Assurance Committee.
Subjects reported to the laboratory in a fasting state at 8 AM and a blood sample was drawn. The blood constituents measured (as described below) were those associated with CAD and NIDDM, and were
RESULTS
Table I shows the descriptive statistics for the subgroups and total sample. Table II shows that the percentage of body fat was inversely correlated with peak V̇O2, and was positively correlated with the atherogenic index and triglyceride levels. The most striking finding was the magnitude of the correlation between percentage of body fat and insulin. The Figure shows that insulin values appeared to increase especially sharply in some children at a fatness level of about 35%. The percentage of
DISCUSSION
The main conclusion from this study is that the DEXA-derived measurement of body fatness is correlated with risk factors for CAD and NIDDM. Our correlations of fatness to the lipid levels are consistent in direction, but greater in magnitude, than those of other studies that used skin folds to measure fatness (e.g., references 9, 19, and 20). The strength of the correlations is probably related to the large number of obese children in our sample. The relations between fatness and risk factors
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From the Department of Pediatrics, Georgia Prevention Institute, and the Department of Medicine, Medical College of Georgia, Augusta.
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Supported in part by the Medical College of Georgia Research Institute and Department of Pediatrics, and by the American Heart Association-Georgia affiliate.
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Reprint requests: Bernard Gutin, PhD, Professor of Pediatrics and Physiology, Georgia Prevention Institute, Medical College of Georgia, Augusta, GA 30912-3710.
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0022-3476/94/$3.00 + 0 9/20/59061