Chest
Special ReportRespiratory Muscles: The Vital Pump
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ACKNOWLEDGMENT
Many individuals collaborated in the work reported in this paper. They include Drs. Ch. Roussos, A. Grassino, D. Gross, A. Peloquin, G. Zagelbaum, C. Cohen and E. Donevan.
REFERENCES (9)
- et al.
Diaphragmatic fatigue in man
J Appl Physiol
(1977) - et al.
Fatigue of inspiratory muscles and their synergic behaviour
J Appl Physiol
(1979) - et al.
The relationship of oxygen cost of breathing to respiratory mechanical work and respiratory force
J Clin Invest
(1961) - Donevan E, Trippenbach T, Grassino A, Macklem PT, Roussos C: Effect of isometric diaphragmatic contraction on cardiac...
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