Abstract
In skeletal muscle, the concentration of Na+/K(+)-pumps is high and increases through training. In isolated muscles, contractile endurance depends in part on Na+/K(+)-pump concentration. Exercise leads to rundown of Na+/K(+)-gradients, compound action potentials, and force. Early and efficient activation of the Na+/K(+)-pump, however, protects excitability and contractility.
MeSH terms
-
Action Potentials / physiology
-
Animals
-
Dogs
-
Exercise / physiology*
-
Humans
-
Membrane Potentials / physiology
-
Mice
-
Muscle Contraction / physiology*
-
Muscle Fatigue / physiology
-
Muscle, Skeletal / metabolism
-
Muscle, Skeletal / physiology*
-
Physical Education and Training
-
Physical Endurance
-
Potassium / blood
-
Potassium / physiology
-
Ranidae
-
Rats
-
Sodium / blood
-
Sodium / physiology
-
Sodium-Potassium-Exchanging ATPase / metabolism
-
Sodium-Potassium-Exchanging ATPase / physiology*
-
Time Factors
Substances
-
Sodium
-
Sodium-Potassium-Exchanging ATPase
-
Potassium