Abstract
Topical application, 4 times daily for 2 weeks, of the diclofenac-hyaluronan gel to 59 osteoarthritis patients induced a significantly greater (p = 0.057) analgesic effect than placebo gel lacking the active substance applied to 60 control patients.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Administration, Oral
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Administration, Topical
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Analgesics / therapeutic use
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
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Diclofenac / therapeutic use*
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Gels
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Humans
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Hyaluronic Acid / therapeutic use*
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Osteoarthritis / drug therapy*
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Osteoarthritis / physiopathology
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Pain
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Palliative Care*
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Time Factors
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Treatment Outcome
Substances
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Analgesics
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Anti-Inflammatory Agents, Non-Steroidal
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Gels
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Diclofenac
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Hyaluronic Acid