Bone mineral changes in young women with hypothalamic amenorrhea treated with oral contraceptives, medroxyprogesterone, or placebo over 12 months
AC Hergenroeder, EOB Smith, R Shypailo… - American journal of …, 1997 - Elsevier
OBJECTIVES: The objectives of this study were to assess (1) whether treatment with oral
contraceptives, in comparison with medroxyprogesterone and placebo, improved bone
mineral in women with hypothalamic amenorrhea and (2) whether treatment with
medroxyprogesterone, in comparison with placebo, improved bone mineral in women with
hypothalamic oligomenorrhea. STUDY DESIGN: The study was a randomized, controlled
clinical trial. Twenty-four white women, aged 14 to 28 years, with hypothalamic amenorrhea …
contraceptives, in comparison with medroxyprogesterone and placebo, improved bone
mineral in women with hypothalamic amenorrhea and (2) whether treatment with
medroxyprogesterone, in comparison with placebo, improved bone mineral in women with
hypothalamic oligomenorrhea. STUDY DESIGN: The study was a randomized, controlled
clinical trial. Twenty-four white women, aged 14 to 28 years, with hypothalamic amenorrhea …