Bone density recovery after depot medroxyprogesterone acetate injectable contraception use
AM Kaunitz, R Arias, M McClung - Contraception, 2008 - contraceptionjournal.org
Background While depot medroxyprogesterone acetate (DMPA) is a highly effective
contraceptive used by millions of women, its use is associated with bone mineral density
(BMD) loss, raising concerns about long-term risk of osteoporosis and/or fractures. Study
Design We conducted a systematic review of studies published in PubMed from 1996 to
2006, evaluating changes in BMD after discontinuation of DMPA. Ten primary clinical or
observational studies were identified addressing this issue. Results BMD consistently …
contraceptive used by millions of women, its use is associated with bone mineral density
(BMD) loss, raising concerns about long-term risk of osteoporosis and/or fractures. Study
Design We conducted a systematic review of studies published in PubMed from 1996 to
2006, evaluating changes in BMD after discontinuation of DMPA. Ten primary clinical or
observational studies were identified addressing this issue. Results BMD consistently …