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Physical training is generally considered to increase serum high density lipoprotein cholesterol (HDL-C) levels.1 However, how exhaustive training influences serum HDL-C levels remains unknown. Intense exercise increases oxygen consumption and free radical formation, and induces oxidation of low density lipoprotein (LDL).2 HDL plays an important protective role in LDL oxidation.3 An imbalance between free radical production and antioxidants is considered to lead to oxidation of LDL and subsequent alterations in serum HDL metabolism. This study investigates changes in serum urate, which is the most important intrinsic antioxidant,4 and serum lipids in male athletes after three weeks of exhaustive training.
We measured fasting serum lipids …