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Endocannabinoids and exercise
  1. A Dietrich1,
  2. W F McDaniel2
  1. 1Department of Social and Behavioral Sciences, American University of Beirut, Lebanon
  2. 2Georgia College and State University, Milledgeville, GA, USA
  1. Correspondence to:
 Dr Dietrich
 PO Box 11-0236, Riad El-Solh, Beirut 1107-2020, Lebanon; arnedietrich{at}
 Dr McDaniel
 Georgia College and State University, Milledgeville, GA 31061, USA; bill.mcdaniel{at}


Exercise induces changes in mental status, particularly analgesia, sedation, anxiolysis, and a sense of wellbeing. The mechanisms underlying these changes remain unknown. Recent findings show that exercise increases serum concentrations of endocannabinoids, suggesting a possible explanation for a number of these changes. This article provides an overview of this emerging field.

  • 2-AG, sn-2-arachidonylglycerol
  • THC, tetrahydrocannabinol
  • anandamide
  • analgesia
  • anxiety
  • marijuana
  • running

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