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Hyperinsulinaemia, hyperaminoacidaemia and post-exercise muscle anabolism: the search for the optimal recovery drink
  1. A H Manninen
  1. Advanced Research Press, Inc, Setauket, NY, USA
  1. Correspondence to:
 Dr Manninen
 Advanced Research Press, Inc, 690 Route 25A, Setauket, NY 11733, USA; sportsnutrition{at}


Dietary supplements and other ergogenic aids are popular among athletes. Recent studies have shown that nutritional mixtures containing protein hydrolysates, added leucine, and high-glycaemic carbohydrates greatly augment insulin secretion compared with high-glycaemic carbohydrates only. When post-exercise hyperinsulinaemia is supported by hyperaminoacidaemia induced by protein hydrolysate and leucine ingestion, net protein deposition in muscle should occur. Thus, consumption of post-exercise recovery drinks containing these nutrients in conjunction with appropriate resistance training may lead to increased skeletal muscle hypertrophy and strength. However, the long-term effects on body composition and exercise performance remain to be determined.

  • CHO, carbohydrate
  • IGF-I, insulin-like growth factor I
  • amino acids
  • protein hydrolysate
  • leucine
  • sports nutrition
  • ergogenic aids

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  • Published Online First 1 September 2006

  • Competing interests: The author is a consultant to BioQuest Pharmaceuticals, Inc.