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TREATMENT OF CHRONIC ELBOW TENDINOSIS WITH BUFFERED PLATELET-RICH PLASMA
Mishra A, Pavelko T. Am J Sports Med 2006;34:1774–8
A small percentage of patients with chronic epicondylar tendinosis of the elbow do not respond to non-operative treatment; however, many are still considering non-operative treatment options.
Does local infiltration with buffered platelet-rich plasma reduce pain and increase function in patients suffering from chronic severe elbow tendinosis who are considering surgery?
20 of 140 patients presenting with chronic elbow epicondylar pain that has not responded to non-operative treatment following a standardised physical therapy protocol and other non-operative treatments.
20 patients with significant persistent (mean 15 months) pain (mean of 82; 60–100 pain on VAS 0–100 scale) and who were considering surgery were allocated in a non-randomised fashion to either a single percutaneous injection of platelet-rich plasma (PRP = 15) or bupivacaine (LA group = 5). Subjects were assessed before and after 1, 2 and 6 months after intervention.
Measures of outcome:
Pain (VAS 0–100), elbow function (Mayo elbow score, best = 100).
3 of the 5 subjects in the LA group withdrew or sought other treatments after the 8-week period, which prevented further analysis.
Subjects in the PRP group reported significantly higher Mayo elbow scores at 2 months compared with the LA group.
In a non-randomised pilot study, treatment …
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