Article Text

Download PDFPDF
Relationship between knee joint laxity and knee joint mechanics during the menstrual cycle
  1. S-K Park1,
  2. D J Stefanyshyn1,
  3. B Ramage2,3,
  4. D A Hart3,
  5. J L Ronsky1,3,4
  1. 1
    Human Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada
  2. 2
    Riddell Movement Assessment Centre, Alberta Children’s Hospital, Calgary, Alberta, Canada
  3. 3
    McCaig Institute for Bone & Joint Health, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
  4. 4
    Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, Calgary, Alberta, Canada
  1. Dr D J Stefanyshyn, Human Performance Laboratory, University of Calgary, 2500 University Drive, NW, Calgary, Alberta T2N 1N4, Canada; darren{at}


Background: An increase in knee laxity during the menstrual cycle may increase the risk of anterior cruciate ligament injury.

Objective: To investigate whether changing knee laxity during the menstrual cycle correlates with changing knee joint loads in a cutting manoeuvre.

Design: Cross-sectional study.

Setting: Laboratory testing.

Participants: 25 healthy women, with a normal menstrual cycle, no history of oral contraceptive use, and no previous knee injury

Interventions: Serum hormone concentrations were assessed and knee joint laxity at a load of 89 N was measured during the follicular, ovulation and luteal phases. Participants performed 10 trials of a cutting manoeuvre to quantify knee joint mechanics at each test session.

Main outcome measurements: Knee joint laxity (mm), peak knee angle (°) and knee joint moment (Nm) and knee joint impulse (Nms).

Results: Increased knee laxity was observed during ovulation compared with the luteal phase, but no significant changes in knee mechanics corresponding to menstrual phases were found. A positive correlation was found between changes in knee laxity and changes in knee joint loads (Δmoment or Δimpulse) from the follicular phase to ovulation, and from ovulation to the luteal phase (p<0.05). Women in whom knee laxity increased showed increased knee loads, and those in whom knee laxity decreased showed decreased knee loads during the menstrual cycle.

Conclusions: Knee laxity correlates positively with knee joint loads, and increased knee laxity during the menstrual cycle may be a potential risk factor for anterior cruciate ligament injuries in certain women during sports activity.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Funding: This work was supported by the Institute of Gender and Health (IGH) of the Canadian Institutes of Health Research (CIHR).

  • Competing interests: None.

  • Ethics approval: This protocol was approved by the Office of Medical Bioethics at the University of Calgary (Grant ID: 18200, 10 March 2005).

  • Patient consent: Obtained.

Linked Articles