Article Text

Download PDFPDF
Effects of acute supplementation with Rhodiola rosea and L-carnitine on exercise performance, cognitive function and cortisol in healthy active volunteers
  1. D Muñiz-Pumares,
  2. A Lage-Guede,
  3. A Firth-Clark,
  4. J Allgrove
  1. Centre for Sport Science and Human Performance, School of Science, University of Greenwich, Chatham Maritime, Kent


Rhodiola rosea (RR) is an adaptogenic herb suggested to improve exercise and cognitive performance and reduce stress responses. Further, some evidence reports that L-carnitine (LC) can alter metabolism during exercise and improve performance. This study examined the effects of acute ingestion of a commercially available RR beverage (250 mg, 3% Rosavin) with and without LC (500 mg) on exercise performance, cognitive function and salivary cortisol. In a double-blind, randomised, crossover-design, 18 healthy, active men and women (age, 21±6 years; maximal oxygen uptake, VO2max 43±9 ml/min/kg) consumed 250 ml of a RR-LC, RR and placebo beverage 45 min before a cycle to fatigue at 77±11% of VO2max. Immediately before and after exercise, computerised cognitive tasks of Rapid Visual Information Processing (RVP), Visual Recognition Memory (VRM) and Stroop Colour-Word (Stroop) were completed. Expired gas and heart rate were recorded continuously during exercise. Capillary blood samples were taken for lactate analysis 2 min after cycling and saliva samples were collected before beverage ingestion, before and immediately after cognitive tests for cortisol analysis. Data were analysed using repeated measures ANOVAs with significance set at P<0.05. Time to fatigue, physiological and cognitive variables did not differ between treatments. Cortisol increased (P=0.028) after tests, but there was no effect of treatment on this response. However, exercise elicited higher RVP sustained attention (P<0.05), a faster response time in Stroop (P<0.05), but VRM was reduced. These findings suggest that acute RR-LC ingestion does not alter cognitive function, exercise performance or salivary cortisol. However, chronic supplementation or greater dosage might affect these results. These results show that exhaustive exercise reduces reaction time and increases attention, but memory outcomes become decreased.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.