Article Text

Download PDFPDF
Long QT syndrome, implantable cardioverter defibrillator (ICD) and competitive sport participation: when science overcomes ethics
  1. Antonio Pelliccia
  1. Institute of Sport Medicine and Science, Rome, Italy
  1. Correspondence to Dr Antonio Pelliccia, Institute of Sport Medicine and Science, Largo Piero Gabrielli, 1, Rome 00197, Italy; ant.pelliccia{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

We saw with great interest the article “Return to play? Athletes with congenital long QT syndrome” recently published in this journal,1 describing the outcome of adolescents with long QT syndrome (LQTS) exposed to regular exercise training and sport participation for a 5-year period.

The authors claim that this experience represents ground for the revision of existing criteria of the Bethesda Conference (BC) #36 and European Society of Cardiology (ESC) recommendations regarding sport participation of young patients with LQTS.2 ,3 For this reason, we believed it appropriate to articulate pertinent considerations relative to their unique experience.

The novel observation refers to LQTS genotype-positive–phenotype-negative asymptomatic children actively involved in varied sport programmes. None incurred adverse events or developed cardiac symptoms in the 5-year period, supporting the substantial benign nature of this condition. This observation substantiates the clinical perception that gene abnormality, per se, should not be viewed as disease and, by showing the absence of significant risk for individuals with no symptoms and normal QTc interval (mean, 0.44 s in this subset), reassures clinicians of the favourable outcome of these young ‘patients’.

The present experience supports the concept that participation in sport activities (at youth league and high-school) does not convey increased risk and is not associated with the occurrence of adverse events in …

View Full Text


  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.

Linked Articles