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Exercise for osteoarthritis of the knee (PEDro synthesis)
  1. Tiê Parma Yamato1,
  2. Leticia A Deveza2,
  3. Chris G Maher1
  1. 1The George Institute for Global Heath, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia
  2. 2Rheumatology Department, Royal North Shore Hospital and Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, New South Wales, Australia
  1. Correspondence to Dr Tiê Parma Yamato, The George Institute for Global Heath, Sydney Medical School, University of Sydney, P.O. Box M201, Missenden Rd, Sydney, NSW 2050, Australia; tyamato{at}

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This section features a recent systematic review that is indexed on PEDro, the Physiotherapy Evidence Database ( PEDro is a free, web-based database of evidence relevant to physiotherapy.

▸ Fransen M, McConnell S, Harmer AR, et al. Exercise for osteoarthritis of the knee. Cochrane Database Syst Rev 2015;1:CD004376.


Osteoarthritis (OA) is the most common form of arthritis, affecting primarily the articular cartilage and the subchondral bone of synovial joints. The prevalence of symptomatic knee OA ranges from 10% to 30% among older individuals worldwide.1 Typical symptoms include joint stiffness and activity-related pain, which may aggravate over time and result in more persistent pain, limited joint function and reduced physical fitness. Therapeutic exercise aims to improve muscle strength, joint range of motion and aerobic fitness and thereby improve OA-related pain, function and quality of life.


To determine the effectiveness of land-based therapeutic exercise in improving pain, function and quality of life for people with knee OA.

Searches and inclusion criteria

Five electronic databases were searched up to May 2013. Randomised or quasi-randomised controlled trials that enrolled individuals treated with land-based therapeutic exercise compared to a no-exercise or a no-treatment control group were included. Adults with an established diagnosis of knee OA according to accepted criteria,2 or who self-reported …

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  • Contributors TPY, LAD and CGM selected the systematic review, interpreted the data, and wrote the manuscript.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.