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Effects of regular physical exercise training in adults with chronic kidney disease (PEDro synthesis)
  1. Kevin Phan1,2,
  2. Fangzhi Jia2,
  3. Steven J Kamper3
  1. 1The NeuroSpine Surgery Research Group (NSURG), Sydney, New South Wales, Australia
  2. 2The University of Sydney, Sydney, New South Wales, Australia
  3. 3Musculoskeletal Division, The George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia
  1. Correspondence to Dr Steven J Kamper, Musculoskeletal Division, The George Institute for Global Health, P.O. Box M201, Sydney, NSW 2050, Australia; skamper{at}

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This section features a recent systematic review that is indexed on PEDro, the Physiotherapy Evidence Database ( PEDro is a free, web-based database of evidence relevant to physiotherapy.


Chronic kidney disease (CKD) is a progressive disease characterised by a gradual loss of renal function over time which can result in renal anaemia and skeletal muscle disorder. Reduced physical functioning and performance often interferes with the performance of daily activities among people with CKD. Physical exercise training may enhance physical functioning for people with CKD.


This systematic review and meta-analysis1 assessed the effects of exercise training in patients with CKD and renal transplant. The secondary aim was to investigate the effects of variation in training programme design.

Search and inclusion criteria

Thirteen databases (including Cochrane Renal Group's register, MEDLINE, EMBASE, CENTRAL, CINAHL) were comprehensively searched. This was supplemented by handsearches of the reference lists of included studies and conference proceedings’ abstracts from nephrology scientific meetings in CENTRAL. There were no language restrictions.

All randomised controlled trials (RCTs) and quasi-RCTs …

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  • Correction notice This paper has been amended since it was published Online First. The wording “PEDro synthesis” has been added to the end of the paper's title.

  • Contributors KP, FJ and SJK interpreted the systematic review, wrote and reviewed drafts. All authors accepted the final version.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.