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In their excellent study1 based on eight British population-based surveys, Perrault and coworkers report on a direct association between alcohol consumption and cancer mortality risk starting from drinking within guidelines versus hazardous drinking and that this association was attenuated among individuals who met the physical activity recommendations. The authors concluded that there are several biological mechanisms by which alcohol is believed to contribute to carcinogenesis, and that the preventive effect of physical activity originates from affecting the same processes, but driving the responses in the opposite direction.
Manipulation of oxidative stress and inflammatory …
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.