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What did I do?
I investigated the effects of heat stress and nutrition strategies on gastrointestinal and associated systemic disturbances during endurance running. I aimed to identify the effect of heat stress on gastrointestinal perturbations during prolonged running and subsequently explore the effectiveness of nutrition prevention strategies.
Why did I do it?
Gastrointestinal disturbances are common during endurance running events affecting ≥60% of athletes and may contribute to impaired nutrition intake, poor performance and withdrawal from competition.1 2 The greatest prevalence of gastrointestinal and associated systemic disturbances (eg, endotoxaemia and cytokinaemia) has been reported during endurance running (≥2 hours of running at ≥60% maximal oxygen uptake (VO2max)) events held in the heat.1 No studies had previously explored the effects of heat exposure during endurance running on gastrointestinal symptoms and/or in conjunction with gastrointestinal integrity, systemic endotoxaemia and cytokinaemia. Further, research on prevention strategies targeting the underlying primary mechanisms, such as hyperthermia …
Contributors RMJS developed the manuscript based on research from her PhD which was conducted under the supervision of Dr Ricardo Costa.
Funding These studies were supported by a Monash University, Faculty of Medicine, Nursing and Health Sciences, Faculty Strategic Grant Scheme SGS15-0128 and a 2015 Sports Medicine Australia Research Foundation Grant.
Patient consent Obtained.
Ethics approval Monash University Human Ethics Research Committee.
Provenance and peer review Not commissioned; internally peer reviewed.
Author note All food and fluid provided in these studies were formulated in-house to produce equivalent solutions that only varied in macronutrient content (hydrolysed whey protein vs glucose-based carbohydrate).
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