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Can a healthcare intervention appear to have a substantial impact on an important outcome metric without really making a difference?
Understanding whether an intervention can really increase the likelihood of a positive outcome is essential when translating research findings into clinical practice. Selectively reporting outcome metrics in randomised controlled trials (RCTs) can mislead readers to believe that a healthcare intervention is more effective than it truly is. Interpreting whether healthcare interventions should be prescribed by clinicians requires not only critical appraisal by the reader, but also transparent reporting of outcome metrics by researchers.1 This seems like the proverbial ‘no brainer’, particularly as there are recommendations for reporting outcome measures.2
Best practice journal policy requires that RCTs must be registered and have their outcome domains (eg, injury), outcome measures (eg, injury risk) and associated outcome metrics (eg, relative risk) listed very specifically.2 Sadly, journal editors rarely police these reporting behaviours so investigators can, and do, choose to selectively present their most compelling results in the most impressive manner. Cherry-picking outcome metrics can mislead the reader (and/or policy maker) to think that an intervention ‘worked’ very effectively when it fact it only worked to some extent.
An impactful intervention? Not so fast! Uncovering the relative and absolute effects of RCTs in sport and exercise medicine
Consider the following worked example: Using an RCT design, investigators compared the risk of sustaining a …
Footnotes
Twitter @markroecoach, @EamonnDelahunt, @peanutbuttner
Contributors MR: conceptual idea of the manuscript, writing of the manuscript and editing of the finaldraft. ED: writing of the manuscript and editing of the final draft. FB: writing of the manuscript and editing of the final draft.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; externally peer reviewed.