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Effects of high-intensity interval training (HIIT) and sprint interval training (SIT) on fat oxidation during exercise: a systematic review and meta-analysis
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    About data collection process, statistical analysis and interpretation of the reported findings

    I read with great interest the study by Atakan et al., (2022) where they summarize existing evidence regarding the effect of high intensity interval training (HIIT) and sprint interval training (SIT) over fat oxidation during sub-maximal intensity exercise. An impaired fat oxidation is a common feature of patients with obesity and type 2 diabetes. Thus, this meta-analysis provides novel information that could be used by physicians and personal trainers to improve the metabolic health of the above mentioned populations. In this rapid response, I discuss several issues regarding data collection process, statistical modelling and interpretation of the reported findings that raised up after a deep analysis of the studies included in this meta-analysis.

    The first meta-analysis of this study evaluated the effect of HIIT/SIT over exercise fat oxidation, summarizing the data from nine studies (Fig. 1). The findings of this meta-analysis are reported in g/min, nevertheless, Arad et al. (60) reported fat oxidation (Fox) relative to fat-free mass (mg∙kg FFM-1∙ min-1), Nybo et al. (30) reported Fox in kJ/min while Zapata-Lamana et al. (64) reported the relative contribution of lipids to energy expenditure. Of note, the authors do not report to request the fat oxidation in g/min from these studies (see data extraction section). Then, ¿How did the authors computed Fox in g∙min-1?

    Otherwise, Astorino et al. (44) and Schubert et al (33), evaluated the effect of both HIIT a...

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    Conflict of Interest:
    None declared.