Objective: To analyze the impact of an off-road motocross heat on plasma levels of oxidative stress and damage, blood leukocyte counts and urine catecholamine concentration.
Methods: Plasma contents of total (TGSH), reduced (GSH), oxidized (GSSG) glutathione, %GSSG, malondialdehyde (MDA), protein carbonyl and –SH groups, total antioxidant status (TAS) and uric acid (UA) as well as blood neutrophil and lymphocyte counts were evaluated in ten male top-level riders before, immediately and one hour after a simulated competitive motocross race. 24-hours urine adrenaline, noradrenaline and dopamine concentrations were also measured.
Results: Motocross heat resulted in an increase in plasma oxidative stress and damage (p<0.05). This was observed by significant increase in %GSSG, TAS, MDA and carbonyls as well as by decrease in –SH after the race. There was a significant increase in both plasma UA and urine catecholamine concentration after the race (p<0.05). Blood neutrophil counts increased at zero and one hour after exercise (p<0.05). Lymphocyte counts increased from baseline to zero hours, although decreased from baseline and zero to one hour post exercise (p<0.05).
Conclusion: The data reinforce the notable metabolic and hormonal demands imposed by motocross, resulting in a condition of enhanced plasma oxidative stress and damage.
- free radicals
- lipid peroxidation
- protein oxidation
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