You are here

  • Home
  • Online First
  • Exercise does not ‘wear down my knee’: systematic reviews and meta-analyses

Article Text

Article menu

other Versions

Download PDFPDF
PhD Academy Award
Exercise does not ‘wear down my knee’: systematic reviews and meta-analyses
  1. Alessio Bricca
  1. Correspondence to Alessio Bricca, Research Unit for Musculoskeletal Function and Physiotherapy, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense 5230, Denmark; alessio.bricca{at}abdn.ac.uk

https://doi.org/10.1136/bjsports-2018-099705

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    What did I do?

    I investigated the impact of exercise on knee joint articular cartilage. This aim was investigated in three different systematic reviews (SRs) of randomised controlled trials (RCTs) in healthy animals and in humans at risk of or with knee osteoarthritis (OA).

    Why did I do it?

    Exercise is the first-line treatment for knee OA.1 Yet, many people still believe that exercise may ‘wear down my knee’ creating a barrier to exercise.

    Articular cartilage is the hallmark of OA and the structure I studied in my PhD. It is a connective tissue that covers bone ends in the joints and provides lubrication of the meeting surfaces, allowing the transmission of loads with a low frictional coefficient. Aggrecan, collagen and molecular biomarkers are the molecules responsible for maintaining cartilage integrity, function and metabolism, and …

    View Full Text

    Footnotes

    • Funding This study is funded by European Union Seventh Framework Programme (FP7-PEOPLE-2013-ITN; KNEEMO) (607510).

    • Competing interests None declared.

    • Patient consent Not required.

    • Provenance and peer review Not commissioned; internally peer reviewed.